Melatonin is produced primarily in the pineal gland but also in the bone marrow, platelets, GI tract, eyes, skin and lymphocytes. It’s chemical precursor is serotonin, a neurotransmitter derived from tryptophan. Serotonin must be acetylated and methylated to form melatonin. Synthesis and production of melatonin is affected by light exposure to the eyes; serum concentrations of melatonin are typically low during the day hours and increase when dark. Since it has important effects in affecting circadian rhythms, melatonin has been reported to have significant effects on sleep-wake cycles and antioxidant function.
Melatonin is produced by the pineal gland that plays a key role in regulating the body’s circadian rhythms and induction of sleep. It plays an essential role in regulating the sleep cycles, and when supplemented, can be helpful for those who have irregular sleep patterns. This formulation is available as 1 mg tablets for flexible dosing.
1 or more tablets per day or as recommended by your health care professional.